The utility model discloses a self-walking sprayer with a spraying rod, comprising a chassis, and a driving system and a spraying system which are arranged on the chassis, wherein the chassis comprises a frame, a front wheel and a rear wheel; the driving system comprises an engine, a speed-changing box and a differential; the spraying system comprises a medicine box and a spraying device; the engine is arranged at the upper part of the rear end of the frame; the speed-changing box is connected with the engine; the differential is connected with the speed-changing box by a transmission shaft and is hinged at the frame by a front suspending mechanism; the front wheel is connected with the differential by a transmission mechanism; the rear wheel is hinged at the frame by a rear suspending mechanism; and the medicine box is arranged at the upper part of the front end of the frame. In the self-walking sprayer, the medicine box is arranged in the front, and the result of adopting the front wheel to drive and the rear wheel to walk is as follows: not only the distribution is reasonable and the structure is compact, but also the operation is flexible and convenient, the slope climbing effect is good and the running is stable.