The utility model relates to a turbine expansion refrigeration device for processing chemical oxidized tail gases. A turbine body is connected with a turbine end, a machine part air filter pressure relief valve and an air compression end, an oxidized tail gas refrigeration channel is formed by the turbine end, a turbine end inlet and a turbine end outlet, and a lubricant channel of a turbine is formed by the turbine end and an oil supply system. The turbine end inlet is connected with waste-heat excess-pressure oxidized tail gases, the turbine end outlet is connected with oxidized tail gases which go to a separator and a cooling box, an air compression end inlet is connected with oxidized tail gases which come from the cooling box and the separator, and an air compression end outlet outputs processed oxidized tail gases. Pressurized lubricant enters the turbine body through a lubricating oil pipe, and purification wind also enters the turbine body to prevent oxidized tail gases from entering a turbine expander and flows back to an oil tank along with the lubricant to be drained. The device has the advantages of being widely applicable to refrigeration processing of various oxidized tail gases of the chemical industry, obvious in refrigeration effect, good in environmental adaptation, simple in structure, safe, reliable, low in energy consumption and high in efficiency.