The utility model relates to an intelligent management box of ground wires of a transformer station, wherein the intelligent management box comprises a box body. The intelligent management box is characterized in that the box body is separated into a plurality of interlayers by diaphragm plates; each of the interlayers is used for placing a pair of ground wires; and each pair of ground wires correspond to a ground wire detection latching mechanism. A glass observation window is inlaid at a box door at the front side of the box body. A ground wire management host is arranged inside the box body and is connected with an anti-error host in an anti-error system by a data line; and the ground wire detection latching mechanism is connected with the ground wire management host by a communication interface. Compared with the prior art, the provided intelligent management box has the following beneficial effects: a solution scheme of intelligent microcomputerized integrated management is introduced for operation ground wires, thereby completely solving a potential safety hazard existing in an operation ground wire production process. A ground wire orientation field prompting function is added, thereby indicating the field leaving grounding point amount and locations. And the embedded ground wire management host with a touch function is installed at the management box, so that performances of visual operation and convenience are realized.