The utility model discloses a ball press machine for powder ball pressing. The ball press machine for powder ball pressing comprises a conveying helix, an extruder, a pressurizing sleeve, forming rollers and a vacuum system, wherein the conveying helix is connected with the extruder through a vacuum cabin; the vacuum cabin is connected with the vacuum system, so that the interiors of the conveying helix and the extruder are vacuum states; the pressurizing sleeve is arranged at the outlet of the extruder; the pressure of a material inside the pressurizing sleeve is higher than 4MPa; the outlet of the pressurizing sleeve is arranged between two forming rollers in pair. According to the ball press machine for powder ball pressing, the material can be pressed inside the pressurizing sleeve by using the extruder, the pressing process does not need very large power like that of an ordinary ball pressing machine, and due to vacuuming, no air needs to be exhausted when a material rod is pressed, and the material can be easily and tightly pressed; the material rod can be cut into spheres through the forming rollers without very large power; multi-screw parallel connection can be achieved according to demands of yield.