The utility model relates to a gas -liquid linkage drive arrangement suitable for main steam isolation valve specifically is the gas -liquid linkage drive arrangement who involves high temperature, high -pressure ultra -large diameter quick closedown (quick closedown in 2~5s) main steam isolation valve, belongs to machinery. It includes hydraulic pressure module, electrical module, oil tank and the electrical part that sets up on valve bracket, gas -liquid linkage drive arrangement sets up with the valve bracket integration. The utility model discloses a global design that unifies of gas -liquid linkage drive arrangement and valve bracket to adopt the integral module ization design, compact structure, it is small, light in weight.