The utility model discloses a prevent instrument and lose toolbox, comprising a box body and a box cover, be stamped the case lid on the box, it is as an organic whole that box and case lid lid closethe connection, the inside of box is provided with six drive mechanism different in size, install in box and casing cover connection department drive mechanism's upper end, the lower extreme extends to be installed at box bottom plate middle part, box bottom plate inboard is provided with six buttons that the size is the same, six buttons that the size is the same are installed respectively and are served at the lower of drive mechanism, box and case lid lid close inside being equipped with and place the chamber, place the intracavity and place different instruments, the instrument is all placed on the button, emergency switch is installed on one side at the back of box, emergency switch is connected with drive mechanism, this toolbox, the inspection mesh of reminding the recovery of staffinspection tool has been played, the instrument in the working process that can prevent is lost, guarantee developing smoothly of day -to -day work, the correct rate of work has been improved.