The utility model discloses a beta lactamase test paper based on adaptation body and oxidation graphite alkene, it is fast that the purport provides a measuring, and detection method is simple, thereliable test paper of testing result, its technical essential includes the bottom plate, the bottom plate on glass fiber, glass fiber is equipped with nucleic acid aptamer and oxidation graphite alkene composite bed, two tip of glass fiber all are equipped with the paper that absorbs water, and nucleic acid aptamer and oxidation graphite alkene composite bed upper portion cover has the protectionfilm, are equipped with a baffle respectively at two sides of bottom plate.