The utility model discloses a device for catalyzing a chemical reaction of a drug. The device comprises a reaction kettle and a pressure regulating kettle, wherein a material inlet is formed in the top of the reaction kettle; a kettle cover is screwed at the material inlet; a through hole is formed in the middle of the kettle cover; a rotating shaft is arranged in the through hole in a penetratingmanner; a rotating motor is fixedly connected to the end, located on the upper portion of the kettle cover, of the rotating shaft, stirring blades are fixedly connected to the other end of the rotating shaft, a water inlet and a feeding port are formed in the neck of the reaction kettle, a pressurizing port and a pressure reducing port are formed in the two opposite sides of the upper portion ofthe reaction kettle respectively, a pressurizing device is arranged at the pressurizing port, and a pressure reducing device is arranged at the pressure reducing port; wherein the reaction kettle is sleeved with a pressure regulating kettle, the pressure regulating kettle comprises a pressure regulating kettle body, the top of the pressure regulating kettle body is connected with the reaction kettle in a sealed mode, and a pressure regulating opening is formed in one side of the pressure regulating kettle body; the problem that an existing drug chemical reaction device does not have a pressurebuffering and adjusting function is solved.