发明公开
- 专利标题： Spirobenzofuranones, their production and use
- 专利标题（中）： SPIROBENZOFURANONES，其生产和使用
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申请号： EP80301431申请日： 1980-05-01
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公开(公告)号： EP0018830A3公开(公告)日： 1980-12-10
- 发明人: Sugihara, Hirosada , Watanabe, Masazumi , Kawada, Mitsuru , Imada, Isuke
- 申请人： Takeda Chemical Industries, Ltd.
- 专利权人： Takeda Chemical Industries, Ltd.
- 当前专利权人： Takeda Chemical Industries, Ltd.
- 优先权： JP5508279 19790504; JP8055179 19790625
- 主分类号： C07D307/94
- IPC分类号： C07D307/94 ; A61K31/34
摘要：
Novel spirobenzofuranone compounds of the formula:
wherein Ring A represents a benzene ring which is substituted by at least one of carboxyl, lower alkoxycarbonyl, carbamoyl which may be substituted, ureido which may be substituted, thioureido which may be substituted, lower alkylthio, lower alkylsulphinyl, lower alkylsulphonyl, mono- or bis-(β-hydroxyethyl) amino, aminoethyl which may be substituted, cyano and phenyl, and pharmaceutically acceptable salts thereof, have gastric secretion inhibitive, antiinflammatory and analgesic activities, and are of value as drugs. The invention relates to such compounds, to processes for their production and to their use as drugs.
wherein Ring A represents a benzene ring which is substituted by at least one of carboxyl, lower alkoxycarbonyl, carbamoyl which may be substituted, ureido which may be substituted, thioureido which may be substituted, lower alkylthio, lower alkylsulphinyl, lower alkylsulphonyl, mono- or bis-(β-hydroxyethyl) amino, aminoethyl which may be substituted, cyano and phenyl, and pharmaceutically acceptable salts thereof, have gastric secretion inhibitive, antiinflammatory and analgesic activities, and are of value as drugs. The invention relates to such compounds, to processes for their production and to their use as drugs.
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