发明授权
- 专利标题: Production of viral antigens
- 专利标题(中): 生产病毒抗原
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申请号: EP81302947.7申请日: 1981-06-29
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公开(公告)号: EP0043272B1公开(公告)日: 1984-06-13
- 发明人: Stott, Edward James , Thomas, Lewis Hartland , Jebbett, Norma Jean
- 申请人: NATIONAL RESEARCH DEVELOPMENT CORPORATION
- 申请人地址: 101 Newington Causeway London SE1 6BU GB
- 专利权人: NATIONAL RESEARCH DEVELOPMENT CORPORATION
- 当前专利权人: NATIONAL RESEARCH DEVELOPMENT CORPORATION
- 当前专利权人地址: 101 Newington Causeway London SE1 6BU GB
- 代理机构: Goldin, Douglas Michael
- 优先权: GB8021434 19800701
- 主分类号: A61K39/155
- IPC分类号: A61K39/155 ; C12N7/08 ; G01N33/54 ; G01N33/56 ; C12N5/00 ; A61K39/42
摘要:
Antigens specific to respiratory syncytial virus are produced on the surface of cells by: (1) culturing in vitro cells derived from a human or animal mucosa, (2) inoculating the cultured cells with respiratory syncytial virus, and (3) selecting virally infected cells from the culture. The resulting cells or the viral antigen(s) when partially or completely isolated from the cells have immunological and diagnostic uses in respect of infection by respiratory syncytial virus and may be used to isolate viral antibodies. A specific cell strain NM7 produced by this method from bovine nasal mucosal cells has respiratory syncytial virus antigens on its surface and its corresponding, uninfected cell strain NM5 can be infected similarly.
公开/授权文献
- EP0043272A1 Production of viral antigens 公开/授权日:1982-01-06
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