发明授权
- 专利标题: COMPOUNDS SUITABLE FOR TREATMENT OR PROPHYLAXIS OF CARDIAC DISORDERS
- 专利标题(中): 适合治疗或预防心脏病的化合物
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申请号: EP81903188.1申请日: 1981-11-16
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公开(公告)号: EP0065542B1公开(公告)日: 1986-07-23
- 发明人: ERHARDT, Paul W. , BORGMAN, Robert J. , O'DONNELL, John P.
- 申请人: AMERICAN HOSPITAL SUPPLY CORPORATION
- 申请人地址: One American Plaza Evanston, IL 60201 US
- 专利权人: AMERICAN HOSPITAL SUPPLY CORPORATION
- 当前专利权人: AMERICAN HOSPITAL SUPPLY CORPORATION
- 当前专利权人地址: One American Plaza Evanston, IL 60201 US
- 代理机构: Seaborn, George Stephen
- 优先权: US211345 19801128
- 国际公布: WO8201869 19820610
- 主分类号: C07C79/46
- IPC分类号: C07C79/46 ; C07C79/48 ; C07C101/30 ; C07C101/42 ; C07C121/52 ; C07C121/60 ; C07C121/62 ; C07C121/64 ; A61K31/215 ; A61K31/275 ; A61K31/24
摘要:
A method for the treatment or prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting ss-blocking compound of the formula: (FORMULA) wherein R may be lower alkyl, aryl, or aralkyl; n may be an integer from 0 to about 10; x may be an integer from 1 to 3; Ar may be substituted or unsubstituted aromatic; R u may be lower alkyl, or aralkyl; and pharmaceutically accepted salts thereof. Novel compounds possessing short acting ss-adrenergic blocking activity are also disclosed.
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