发明公开
EP0087638A1 Polyprenyl compounds and preparation thereof
失效
Polyprenylverbindungen und deren Herstellung。
- 专利标题： Polyprenyl compounds and preparation thereof
- 专利标题（中）： Polyprenylverbindungen und deren Herstellung。
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申请号： EP83101283.6申请日： 1983-02-10
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公开(公告)号： EP0087638A1公开(公告)日： 1983-09-07
- 发明人: Onishi, Takashi , Suzuki, Shigeaki , Mori, Fumio , Takigawa, Tetsuo , Fujita, Yoshiji , Mizuno, Masao , Nishida, Takashi
- 申请人： KURARAY CO., LTD.
- 申请人地址： 1621 Sakazu Kurashiki-City Okayama Prefecture 710 JP
- 专利权人： KURARAY CO., LTD.
- 当前专利权人： KURARAY CO., LTD.
- 当前专利权人地址： 1621 Sakazu Kurashiki-City Okayama Prefecture 710 JP
- 代理机构： VOSSIUS & PARTNER
- 优先权： JP20855/82 19820211; JP20856/82 19820211
- 主分类号： C07C147/10
- IPC分类号： C07C147/10 ; C07C33/02 ; C07D309/12 ; C07F7/18 ; C07C149/36 ; C07C147/14 ; C07D317/18 ; C07D405/12 ; C07D417/12 ; C07D277/16 ; C07D213/70
摘要：
The invention relates to polyprenyl compounds of the general formula
wherein
represents a trans-isoprene unit,
represents a cis-isoprene unit, n is an integer of 11-19, Z' is -CH 2 0H or a functional precursor thereof, and either one of R' and R 2 is a hydrogen atom and the other is -S(O) m R 3 in which m is an integer of 0 (zero), 1 or 2 and R 3 is a phenyl, naphthyl, pyridyl or thiazolinyl group which may optionally have one or more substituents selected from lower alkyl groups and halogen atoms. These polyprenyl compounds can be synthesized by reacting a compound of the general formula
with a compound of the general formula
with the aid of an anionizing agent.
(either one of A and X being a halogen atom and the other being -S(O) m R 3 )
These polyprenyl compounds can be converted into mammalian dolichols or precursors thereof by reductive elimination of the -S(O) m R 3 group.
wherein
represents a trans-isoprene unit,
represents a cis-isoprene unit, n is an integer of 11-19, Z' is -CH 2 0H or a functional precursor thereof, and either one of R' and R 2 is a hydrogen atom and the other is -S(O) m R 3 in which m is an integer of 0 (zero), 1 or 2 and R 3 is a phenyl, naphthyl, pyridyl or thiazolinyl group which may optionally have one or more substituents selected from lower alkyl groups and halogen atoms. These polyprenyl compounds can be synthesized by reacting a compound of the general formula
with a compound of the general formula
with the aid of an anionizing agent.
(either one of A and X being a halogen atom and the other being -S(O) m R 3 )
These polyprenyl compounds can be converted into mammalian dolichols or precursors thereof by reductive elimination of the -S(O) m R 3 group.
公开/授权文献
- EP0087638B1 Polyprenyl compounds and preparation thereof 公开/授权日：1985-06-05
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