发明公开
EP0102504A1 Ascorbate-resistant broad range glucose test composition, test device and method 失效
对于用于测试葡萄糖,测试设备和方法的宽范围的合适的抗坏血酸性组合物。

  • 专利标题: Ascorbate-resistant broad range glucose test composition, test device and method
  • 专利标题(中): 对于用于测试葡萄糖,测试设备和方法的宽范围的合适的抗坏血酸性组合物。
  • 申请号: EP83107309.3
    申请日: 1983-07-26
  • 公开(公告)号: EP0102504A1
    公开(公告)日: 1984-03-14
  • 发明人: Bauer, Robert
  • 申请人: MILES LABORATORIES, INC.
  • 申请人地址: 1127 Myrtle Street Elkhart Indiana 46514 US
  • 专利权人: MILES LABORATORIES, INC.
  • 当前专利权人: MILES LABORATORIES, INC.
  • 当前专利权人地址: 1127 Myrtle Street Elkhart Indiana 46514 US
  • 代理机构: Dänner, Klaus, Dr.
  • 优先权: US404445 19820802
  • 主分类号: C12Q1/54
  • IPC分类号: C12Q1/54 G01N33/52 G01N33/66
Ascorbate-resistant broad range glucose test composition, test device and method
摘要:
A composition, test device and method for detecting the presence and/or determining concentration of glucose in a liquid test sample are disclosed. The composition is capable of determining glucose concentration over a broad range, e.g. 0 to about 5,000 milligrams (mg) of glucose per deciliter (d1) of test sample. Moreover, the composition is resistant to interference from the presence of ascorbate in the sample. The composition comprises glucose oxidase, peroxidase and, as an indicator capable of producing a detectable response in the presence of peroxidase and H 2 0 2 , a mixture of two compounds. One has the structure
and the other has the structure
in which R, same of different, is H or lower alkyl, R' is aryl and R" is lower alkyl.
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