发明公开
EP0131418A1 Proteins, pharmaceutical compositons, genes, vectors, host organisms and processes for their production
失效
蛋白酶，pharmazeutische Zusammensetzungen，Gene，Vektoren，Wirtorganismen und Verfahren zu deren Herstellung。
- 专利标题： Proteins, pharmaceutical compositons, genes, vectors, host organisms and processes for their production
- 专利标题（中）： 蛋白酶，pharmazeutische Zusammensetzungen，Gene，Vektoren，Wirtorganismen und Verfahren zu deren Herstellung。
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申请号： EP84304469.4申请日： 1984-06-29
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公开(公告)号： EP0131418A1公开(公告)日： 1985-01-16
- 发明人: Williamson, Robert , Carey, Norman Henry
- 申请人： CELLTECH LIMITED
- 申请人地址： 244-250 Bath Road Slough Berkshire SL1 4DY GB
- 专利权人： CELLTECH LIMITED
- 当前专利权人： CELLTECH LIMITED
- 当前专利权人地址： 244-250 Bath Road Slough Berkshire SL1 4DY GB
- 代理机构： Votier, Sidney David
- 优先权： GB8317989 19830701; GB8323759 19830905
- 主分类号： C12N15/00
- IPC分类号： C12N15/00 ; C12P21/02 ; C12N9/20 ; A61K37/54 ; C12N1/16
摘要：
@ A rat or human lingual lipase protein for use in the treatment of lipase deficiency. A process is described for producing lingual lipase using recombinant DNA technoloy to produce a host organism (for example E.coli) capable of producing a precursor of the lingual lipase which may be cleaved to yield the lingual lipase. The host organism is transformed with a vector including a gene coding for the precursor of lingual lipase. The precursor protein is for example prelingual lipase protein, or a fusion protein comprising lingual lipase and a heterologous protein. A pharmaceutical composition in unit dosage or liquid form is described.
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