发明公开
- 专利标题： Alpha-hydroxyketone acetals
- 专利标题（中）： 乙醛樟脑α-羟基酮。
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申请号： EP84113585.8申请日： 1981-09-10
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公开(公告)号： EP0151702A2公开(公告)日： 1985-08-21
- 发明人: Tsuchihashi, Genichi , Mitamura, Shuichi , Kitajima, Kouji
- 申请人： SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED
- 申请人地址： Corner House Church Street Hamilton 5 BM
- 专利权人： SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED
- 当前专利权人： SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED
- 当前专利权人地址： Corner House Church Street Hamilton 5 BM
- 代理机构： Cresswell, Thomas Anthony
- 优先权： JP125355/80 19800911; JP143042/80 19801015; JP157049/80 19801110; JP11700/81 19810130; JP90979/81 19810615
- 主分类号： C07C43/315
- IPC分类号： C07C43/315 ; C07D209/46 ; C07D333/22
摘要：
Alpha-hydroxyketone acetals of the formula:
wherein Ar represents an aromatic group, R 1 represents a hydrogen atom or a saturated aliphatic group, or Ar and R' form a condensed ring together with the carbon atom to which they are bonded, and R 3 and R 4 independently represent alkyl groups or together represent an alkylene group, subject to the proviso that Ar does not represent phenyl or 4-chlorophenyl when R' is a hydrogen atom. The acetals (VI) can be converted into alpha-sulfonyloxyketone acetals and thence into alpha-aromatic group substituted alkanoic acids or esters.
wherein Ar represents an aromatic group, R 1 represents a hydrogen atom or a saturated aliphatic group, or Ar and R' form a condensed ring together with the carbon atom to which they are bonded, and R 3 and R 4 independently represent alkyl groups or together represent an alkylene group, subject to the proviso that Ar does not represent phenyl or 4-chlorophenyl when R' is a hydrogen atom. The acetals (VI) can be converted into alpha-sulfonyloxyketone acetals and thence into alpha-aromatic group substituted alkanoic acids or esters.
公开/授权文献
- EP0151702B1 Alpha-hydroxyketone acetals 公开/授权日：1987-11-25
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