发明公开
EP0175852A2 Method for producing useful substances using genetically engineered viral DNA
失效
一种用于通过使用基因工程改造的病毒DNA的生产有用的物质的过程。
- 专利标题: Method for producing useful substances using genetically engineered viral DNA
- 专利标题(中): 一种用于通过使用基因工程改造的病毒DNA的生产有用的物质的过程。
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申请号: EP85107711.5申请日: 1985-06-21
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公开(公告)号: EP0175852A2公开(公告)日: 1986-04-02
- 发明人: Maeda, Susumu , Furusawa, Mitsuru c/o Daiichi Seiyaku Res. Instit.
- 申请人: DAIICHI SEIYAKU CO., LTD.
- 申请人地址: 14-10, Nihonbashi 3-chome Chuo-ku Tokyo 103 JP
- 专利权人: DAIICHI SEIYAKU CO., LTD.
- 当前专利权人: DAIICHI SEIYAKU CO., LTD.
- 当前专利权人地址: 14-10, Nihonbashi 3-chome Chuo-ku Tokyo 103 JP
- 代理机构: Kinzebach, Werner, Dr.
- 优先权: JP128215/84 19840621
- 主分类号: C12N15/21
- IPC分类号: C12N15/21 ; C12N15/86 ; C12P21/02 ; C12N7/00 ; C07K13/00
摘要:
A method of producing useful substances which comprising propagating in cultured cells or in a host a recombinant Bombyx mori nuclear polyhedrosis virus (BmNPV) DNA is disclosed. The BmNPV DNA is produced by recombination with a double-stranded DNA containing (i) a 5'- upstream BmNPV DNA fragment originally occurring upstream from the structural gene coding for the production of polyhedral protein and also including the promotor region for the structural gene, (ii) a translational start codon and (iii) a gene coding for the production of a useful substance exogenous to the virus, with or without (iv) a 3'-downstream BmNPV DNA fragment originally occurring downstream from the structural gene coding for the production of polyhedral protein.
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