发明公开
EP0175852A2 Method for producing useful substances using genetically engineered viral DNA 失效
一种用于通过使用基因工程改造的病毒DNA的生产有用的物质的过程。

Method for producing useful substances using genetically engineered viral DNA
摘要:
A method of producing useful substances which comprising propagating in cultured cells or in a host a recombinant Bombyx mori nuclear polyhedrosis virus (BmNPV) DNA is disclosed. The BmNPV DNA is produced by recombination with a double-stranded DNA containing (i) a 5'- upstream BmNPV DNA fragment originally occurring upstream from the structural gene coding for the production of polyhedral protein and also including the promotor region for the structural gene, (ii) a translational start codon and (iii) a gene coding for the production of a useful substance exogenous to the virus, with or without (iv) a 3'-downstream BmNPV DNA fragment originally occurring downstream from the structural gene coding for the production of polyhedral protein.
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