发明公开
- 专利标题： Alkylaminofuranone derivatives
- 专利标题（中）： 烷基氨基嘌呤衍生物
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申请号： EP86300895申请日： 1986-02-10
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公开(公告)号： EP0192393A3公开(公告)日： 1988-11-17
- 发明人: Fodor, Tamas , Dobay, Laszlo , Fischer, Janos , Stefko, Bela , Kiss, Bela , Szombathelyi, Zsolt , Karpati, Egon , Laszlovszky, Istavan , Szporny, Laszlo
- 申请人： RICHTER GEDEON VEGYESZETI GYAR R.T.
- 专利权人： RICHTER GEDEON VEGYESZETI GYAR R.T.
- 当前专利权人： RICHTER GEDEON VEGYESZETI GYAR R.T.
- 优先权： HU50485 19850211
- 主分类号： C07K05/06
- IPC分类号： C07K05/06 ; A61K37/02
摘要：
The present invention relates to a compound of formula (I)
wherein
R' represents methyl or a group of the formula R 3 -NH-/CH 2 ) 4 - wherein R 3 is hydrogen or a protective group compatible with the peptide bond, R 2 represents hydrogen, a protective group compatible with the peptide bond or a cation derived from an organic or inorganic base; pharmaceutically acceptable salts and diastereomers thereof. The compounds of the invention are useful for inhibiting the effect of the angiotensin-converting enzyme and they can be used in therapy as blood pressure reducing agents and for the treatment of cardiac failure and glaucoma.
wherein
R' represents methyl or a group of the formula R 3 -NH-/CH 2 ) 4 - wherein R 3 is hydrogen or a protective group compatible with the peptide bond, R 2 represents hydrogen, a protective group compatible with the peptide bond or a cation derived from an organic or inorganic base; pharmaceutically acceptable salts and diastereomers thereof. The compounds of the invention are useful for inhibiting the effect of the angiotensin-converting enzyme and they can be used in therapy as blood pressure reducing agents and for the treatment of cardiac failure and glaucoma.
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