- 专利标题： Pyrroloquinoline quinones as enzyme inhibitors
- 专利标题（中）： 吡咯啉喹啉
-
申请号： EP87111397.3申请日： 1987-08-06
-
公开(公告)号： EP0262345A2公开(公告)日： 1988-04-06
- 发明人: Narutomi, Yuji , Katsumata, Manabu , Osawa, Yasuko , Uchikuga, Saburo
- 申请人： Sogo Pharmaceutical Company Limited
- 申请人地址： 6-2, Ohtemachi 2-chome Chiyoda-ku Tokyo 100 JP
- 专利权人： Sogo Pharmaceutical Company Limited
- 当前专利权人： Sogo Pharmaceutical Company Limited
- 当前专利权人地址： 6-2, Ohtemachi 2-chome Chiyoda-ku Tokyo 100 JP
- 代理机构： Thomsen, Dieter, Dr.
- 优先权： JP184127/86 19860807; JP189542/86 19860814; JP46771/87 19870303; JP185365/87 19870727
- 主分类号： A61K31/475
- IPC分类号： A61K31/475
摘要：
The present invention concerns an enzyme inhibitor containing the compound represented by the following formula (I) as an effective ingredient :
where R represents hydrogen or substituted or not substituted alkyl group, alkenyl group, aryl group or aralkyl group, X represents ORʹ or NRʺR‴, in which Rʹ, Rʺ and R‴ represent respectively hydrogen or substituted or not substituted alkyl group, alkenyl group, aryl group or aralkyl group.
The enzyme inhibitor according to the present invention can effectively inhibit aldose reductase, glyoxalase I and reverse transcriptase.
where R represents hydrogen or substituted or not substituted alkyl group, alkenyl group, aryl group or aralkyl group, X represents ORʹ or NRʺR‴, in which Rʹ, Rʺ and R‴ represent respectively hydrogen or substituted or not substituted alkyl group, alkenyl group, aryl group or aralkyl group.
The enzyme inhibitor according to the present invention can effectively inhibit aldose reductase, glyoxalase I and reverse transcriptase.
公开/授权文献
- EP0262345A3 Pyrroloquinoline quinones as enzyme inhibitors 公开/授权日：1990-09-12
信息查询
IPC分类:
