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1.
公开(公告)号:EP4444319A1
公开(公告)日:2024-10-16
申请号:EP22903713.0
申请日:2022-12-09
IPC分类号: A61K31/7004 , A61K31/194 , A61K31/198 , A61K31/336 , A61K31/475 , A61K31/4995 , A61K31/548 , A61P17/00 , A61P17/06 , A61P17/14 , C12Q1/6869 , C12Q1/6883
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公开(公告)号:EP3884943B1
公开(公告)日:2024-07-17
申请号:EP19887480.2
申请日:2019-11-18
IPC分类号: A61K31/4406 , A61K31/475 , A61K31/573 , A61K31/704 , A61K31/675 , A61K31/44 , A61K39/395 , A61P35/00 , C07K16/28
CPC分类号: A61K31/675 , A61P35/00 , A61K31/704 , A61K31/4406 , C07K16/2887 , A61K2039/50520130101 , A61K39/3955 , A61K31/475 , A61K31/573
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公开(公告)号:EP4393481A1
公开(公告)日:2024-07-03
申请号:EP22885750.4
申请日:2022-10-19
发明人: DENG, Jingjing , XU, Zhongli , LI, Yonghai
IPC分类号: A61K9/12 , A61K31/475 , A61M11/00
CPC分类号: A61K31/475 , A61P15/10 , A61K47/10 , A61K47/12 , A61K9/12 , A61P13/02 , A61M11/04 , A61M11/02 , A61M11/00 , A61K9/0073 , A61K36/74 , A61P13/08 , A61K31/4375
摘要: The present application discloses a liquid preparation, a method for preparing the liquid preparation, an aerosol generation system, a cartridge for the aerosol generation system, and an aerosol generation apparatus. The liquid preparation includes a yohimbine extract, a chaotropic agent and a solvent, where the solubility of the yohimbine extract in the chaotropic agent is greater than the solubility of the yohimbine extract in the solvent; and the yohimbine extract can form a stable and transparent solution with the solvent after being dissolved in the chaotropic agent. The yohimbine extract is dissolved in the chaotropic agent and then mixed with the solvent in the liquid preparation, the use amount of the yohimbine extract in the aerosol generation system is increased by means of dissolving the yohimbine extract in the chaotropic agent, then mixing with the solvent of the liquid preparation, thereby promoting the use of the yohimbine extract in the aerosol generation system.
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公开(公告)号:EP3505555B1
公开(公告)日:2024-01-03
申请号:EP17843643.2
申请日:2017-08-23
发明人: QUADER Sabina , CABRAL Horacio , KINOH Hiroaki , KATAOKA Kazunori
IPC分类号: C08G69/08 , A61K47/59 , A61K31/475 , A61K31/5517 , A61K31/553 , A61P35/00 , C08G69/10 , C08G69/40
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公开(公告)号:EP3773582B1
公开(公告)日:2023-10-25
申请号:EP19717684.5
申请日:2019-04-01
IPC分类号: A61K31/475 , A61P29/00 , A61P35/00
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公开(公告)号:EP3773548B1
公开(公告)日:2023-08-09
申请号:EP19804326.7
申请日:2019-05-15
发明人: SINGER, Jamie , WACHTER, Eric A. , SWIFT, Lucy , ZHANG, Chunfen , TRIPPETT, Tanya , NARENDRAN, Aru
IPC分类号: A61K31/352 , A61K45/06 , A61P35/00 , A61K31/365 , A61K31/4745 , A61K31/475 , A61K31/704 , A61K31/7048 , A61K31/7068 , A61K33/24 , A61K31/343
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公开(公告)号:EP4211145A1
公开(公告)日:2023-07-19
申请号:EP22862412.8
申请日:2022-11-15
发明人: QIN, Gang , ZHANG, Tony, Yantao , CHENG, Guangming , SONG, Paul, H. , ZHONG, Boyu , HU, Mingyu
IPC分类号: C07K7/06 , C07K5/103 , C07D491/22 , A61P35/00 , A61K31/537 , A61K38/07 , A61K47/68 , A61K45/00 , A61K31/165 , A61P37/02 , A61K31/475 , A61K47/65
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公开(公告)号:EP4168048A1
公开(公告)日:2023-04-26
申请号:EP21828391.9
申请日:2021-06-23
申请人: Adagene Pte. Ltd.
发明人: LIU, Guizhong , NGUYEN, Aaron , LUO, Peter Peizhi
IPC分类号: A61K39/395 , A61K31/4184 , A61K31/4406 , A61K31/475 , A61K31/63 , A61K31/69 , A61K38/20 , A61P35/00 , C07K16/38
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公开(公告)号:EP4104830A1
公开(公告)日:2022-12-21
申请号:EP21179848.3
申请日:2021-06-16
申请人: Wittig, Burghardt
发明人: Wittig, Burghardt
IPC分类号: A61K31/282 , A61K31/352 , A61K31/475 , A61K31/713 , A61K33/243 , A61K39/395 , A61P35/00
摘要: The invention relates to the use of TLR9 agonists, and checkpoint modulators in biomarkerled treatment protocols designed to deliver optimal immune modulation signals to cancer patients following an induction chemotherapy treatment with a chemotherapeutic dug.
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公开(公告)号:EP3402527B1
公开(公告)日:2022-09-28
申请号:EP17738859.2
申请日:2017-01-11
发明人: DILUCCIO, Robert
IPC分类号: A61K47/50 , A61K9/51 , A61K31/549 , A61K31/475 , A61K31/704 , A61P35/00
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