发明公开
- 专利标题： Lactam derivatives, processes for the preparation thereof, pharmaceutical compositions comprising the same, and the use of such derivatives for the manufacture of a medicament having valuable therapeutic properties
- 专利标题（中）： LACTAM衍生物，其制备方法，包含其的药物组合物，以及这些衍生物在制备具有可控治疗性质的药物中的用途
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申请号： EP87117822.4申请日： 1987-12-02
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公开(公告)号： EP0270093A3公开(公告)日： 1989-12-27
- 发明人: Sato, Yasuhiko , Yamada, Koichiro , Nomura, Sumihiro , Ishida, Ryuichi , Yamamura, Michio
- 申请人： TANABE SEIYAKU CO., LTD.
- 申请人地址： 2-10, Dosho-machi 3-chome Chuo-ku Osaka JP
- 专利权人： TANABE SEIYAKU CO., LTD.
- 当前专利权人： TANABE SEIYAKU CO., LTD.
- 当前专利权人地址： 2-10, Dosho-machi 3-chome Chuo-ku Osaka JP
- 代理机构： Hansen, Bernd, Dr.rer.nat.
- 优先权： JP288079/86 19861203
- 主分类号： C07D211/76
- IPC分类号： C07D211/76 ; C07D211/72 ; C07D207/26 ; C07D207/24 ; C07D401/04 ; A61K31/435 ; A61K31/40
摘要：
There are disclosed a lactam derivative of the formula:
wherein R 1 is a substituted or unsubstituted phenyl group; R 2 is a substituted or unsubstituted phenyl group, a cycloalkyl group or a nitrogen-containing 6-membered heterocyclic group; Z is oxygen atom or sulfur atom; and n is an integer of 2 or 3, and a salt thereof, and a preparation thereof. The above lactam derivative is novel and useful as a pharmaceutical compound. Accordingly, pharmaceutical preparations are also provided, together with the use of such derivatives for the manufacture of a medicament having valuable therapeutic properties.
wherein R 1 is a substituted or unsubstituted phenyl group; R 2 is a substituted or unsubstituted phenyl group, a cycloalkyl group or a nitrogen-containing 6-membered heterocyclic group; Z is oxygen atom or sulfur atom; and n is an integer of 2 or 3, and a salt thereof, and a preparation thereof. The above lactam derivative is novel and useful as a pharmaceutical compound. Accordingly, pharmaceutical preparations are also provided, together with the use of such derivatives for the manufacture of a medicament having valuable therapeutic properties.
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