发明公开
- 专利标题： DC-52 TYPE ONCOSTATIC COMPOUND
- 专利标题（中）： ONKOSTATISCHE VERBINDUNG VOM DC-52-TYP。
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申请号： EP87906220.6申请日： 1987-09-28
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公开(公告)号： EP0283521A1公开(公告)日： 1988-09-28
- 发明人: SAITO, Hiromitsu , UOSAKI, Yoichi , SATO, Akira , HIRATA, Tadashi , MORIMOTO, Makoto , ASHIZAWA, Tadashi
- 申请人： KYOWA HAKKO KOGYO KABUSHIKI KAISHA
- 申请人地址： 6-1, Ohte-machi 1-chome Chiyoda-ku, Tokyo 100 JP
- 专利权人： KYOWA HAKKO KOGYO KABUSHIKI KAISHA
- 当前专利权人： KYOWA HAKKO KOGYO KABUSHIKI KAISHA
- 当前专利权人地址： 6-1, Ohte-machi 1-chome Chiyoda-ku, Tokyo 100 JP
- 代理机构： Lambert, Hugh Richmond
- 优先权： JP23380186 19861001
- 国际公布： WO1988002369 19880407
- 主分类号： C07D471/18
- IPC分类号： C07D471/18 ; C07D498/22 ; A61K31/495
摘要：
Novel DC-52 derivatives represented by formula (I). These compounds and their pharmaceutically acceptable salts have an excellent oncostatic activity. In the formula, X represents chlorine, bromine, iodine, hydroxy, formyl, hydroxyiminomethyl, cyano, nitro, amino or lower alkanolyamine, Y represents hydroxy, and Z represents cyano, or Y and Z are bound to each other to represent -O- as -Y-Z-.
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