发明公开
EP0316658A1 Infectious bovine rhinotracheitis virus mutants, vaccines containing same, methods for the production of same and methods for the use of same
失效
感染性牛鼻气管炎病毒的突变体，含有它们的疫苗，其制备方法和它们的用途。
- 专利标题： Infectious bovine rhinotracheitis virus mutants, vaccines containing same, methods for the production of same and methods for the use of same
- 专利标题（中）： 感染性牛鼻气管炎病毒的突变体，含有它们的疫苗，其制备方法和它们的用途。
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申请号： EP88118266.1申请日： 1988-11-02
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公开(公告)号： EP0316658A1公开(公告)日： 1989-05-24
- 发明人: Kit, Malon , Kit, Saul , Otsuka, Haruki
- 申请人： NOVAGENE, INC. , BAYLOR COLLEGE OF MEDICINE
- 申请人地址： P.O. Box 270275 Houston Texas 77277 US
- 专利权人： NOVAGENE, INC.,BAYLOR COLLEGE OF MEDICINE
- 当前专利权人： NOVAGENE, INC.,BAYLOR COLLEGE OF MEDICINE
- 当前专利权人地址： P.O. Box 270275 Houston Texas 77277 US
- 代理机构： Hansen, Bernd, Dr.rer.nat.
- 优先权： US116197 19871103
- 主分类号： C12N15/38
- IPC分类号： C12N15/38 ; A61K39/265
摘要：
Infectious bovine rhinotracheitis virus (bovine herpesvirus type 1) mutants containing deletion and/or insertion mutations in a major viral glycoprotein gene, such that no antigenic polypeptides encoded by the viral gene are produced, vaccines for infectious bovine rhinotracheitis containing the same, methods for the production of the same and methods for use of the same. Animals vaccinated with these mutants do not develop antibodies to the viral glycoprotein and can be distinguished serologically from animals infected with infectious bovine rhinotracheitis virus field strains.
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