发明公开
- 专利标题： Sulfonamide compounds
- 专利标题（中）： 磺酰胺-Verbindungen。
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申请号： EP89102586.8申请日： 1989-02-15
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公开(公告)号： EP0330065A1公开(公告)日： 1989-08-30
- 发明人: Tanabe, Sohei , Sato, Seiichi , Kyotani, Yoshinori , Ohta, Tomio , Uchida, Yasumi
- 申请人： KOWA COMPANY, LTD.
- 申请人地址： 6-29, 3-chome Nishiki Naka-ku Nagoya-shi Aichi-ken JP
- 专利权人： KOWA COMPANY, LTD.
- 当前专利权人： KOWA COMPANY, LTD.
- 当前专利权人地址： 6-29, 3-chome Nishiki Naka-ku Nagoya-shi Aichi-ken JP
- 代理机构： Kraus, Walter, Dr.
- 优先权： JP33949/88 19880218
- 主分类号： C07D295/12
- IPC分类号： C07D295/12 ; C07D213/74
摘要：
A sulfonamide compound represented by the following formula
wherein R¹, R² and R³ are identical or different, and each represents a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group; R⁴ represents a hydrogen atom, a lower alkyl group, or a substituted or unsubstituted aralkyl group; R⁵ represents a substituted or unsubstituted aryl group or a substituted or unsubstituted aralkyl group; R⁶ and R⁷ are identical or different and each represents a hydrogen atom, a lower alkyl group or a lower alkoxy group; and n is an integer of 1 to 8,
and an acid addition salt thereof. The compounds of formula (I) provided by this invention have some useful biological activities such as the spasmolytic activity on the vascular smooth muscles and anti-platelet aggregatory activity and are useful as drugs for treating cardiovascular disorders such as angina pectoris, cerebral circulation disorder and thrombosis.
wherein R¹, R² and R³ are identical or different, and each represents a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group; R⁴ represents a hydrogen atom, a lower alkyl group, or a substituted or unsubstituted aralkyl group; R⁵ represents a substituted or unsubstituted aryl group or a substituted or unsubstituted aralkyl group; R⁶ and R⁷ are identical or different and each represents a hydrogen atom, a lower alkyl group or a lower alkoxy group; and n is an integer of 1 to 8,
and an acid addition salt thereof. The compounds of formula (I) provided by this invention have some useful biological activities such as the spasmolytic activity on the vascular smooth muscles and anti-platelet aggregatory activity and are useful as drugs for treating cardiovascular disorders such as angina pectoris, cerebral circulation disorder and thrombosis.
公开/授权文献
- EP0330065B1 Sulfonamide compounds 公开/授权日：1993-11-10
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