发明公开
- 专利标题： New analogues of all-bond retroinverted thymopentin, the method for the synthesis of the same and their employment for the preparation of pharmaceutical compositions
- 专利标题（中）： 全键合抗坏血酸的新型模拟物，其合成方法及其制备药物组合物的使用方法
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申请号： EP90201609.6申请日： 1990-06-20
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公开(公告)号： EP0406931A3公开(公告)日： 1991-07-17
- 发明人: Mariotti, Sabina , Sisto, Alessandro , Nencioni, Luciano , Villa, Luigi , Pessi, Antonello
- 申请人： SCLAVO S.p.A.
- 申请人地址： Via Fiorentina 1 I-53100 Siena IT
- 专利权人： SCLAVO S.p.A.
- 当前专利权人： SCLAVO S.p.A.
- 当前专利权人地址： Via Fiorentina 1 I-53100 Siena IT
- 代理机构： Gervasi, Gemma, Dr.
- 优先权： IT2103789 19890630
- 主分类号： C07K5/02
- IPC分类号： C07K5/02 ; C07K7/02
摘要：
New thymopentin (TP5) analogues whose bonds in the peptide chain are all retro-inverted are disclosed. Such new compounds have the following general formula (I)
wherein R is hydrogen or an acyl radical, and R¹ is a group of the formula -OR², wherein R² is a hydrogen atom or a hydrocarbon radical, and the corresponding basic or acid addition salts which are pharmaceutically acceptable. The new compounds have immunostimulating activity.
wherein R is hydrogen or an acyl radical, and R¹ is a group of the formula -OR², wherein R² is a hydrogen atom or a hydrocarbon radical, and the corresponding basic or acid addition salts which are pharmaceutically acceptable. The new compounds have immunostimulating activity.
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