发明公开
EP0408108A2 Pharmaceutical compositions containing acrylic acid derivatives and their use in the medicine
失效
Acrylsäure-Derivate enthaltende Zusammensetzungen und ihre medizinische Anwendung。
- 专利标题： Pharmaceutical compositions containing acrylic acid derivatives and their use in the medicine
- 专利标题（中）： Acrylsäure-Derivate enthaltende Zusammensetzungen und ihre medizinische Anwendung。
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申请号： EP90201744.1申请日： 1990-06-29
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公开(公告)号： EP0408108A2公开(公告)日： 1991-01-16
- 发明人: Fodor, Tamas , Fischer, Janos , Dobay, Laszlo , Ezer, Elemér , Matuz, Judit , Saghy, Katalin , Szporny, Laszlo , Hajos, György , Trischler, Ferenc
- 申请人： RICHTER GEDEON VEGYESZETI GYAR R.T.
- 申请人地址： Gyömröi ut 19-21 H-1103 Budapest X HU
- 专利权人： RICHTER GEDEON VEGYESZETI GYAR R.T.
- 当前专利权人： RICHTER GEDEON VEGYESZETI GYAR R.T.
- 当前专利权人地址： Gyömröi ut 19-21 H-1103 Budapest X HU
- 代理机构： Kupecz, Arpad
- 优先权： HU357289 19890714
- 主分类号： A61K31/19
- IPC分类号： A61K31/19 ; A61K31/215 ; A61K31/275
摘要：
Known acrylic acid derivatives of formula
wherein
n is an integer of from 0 to 2,
R represents a hydrogen, an alkaline or an alkaline earth metal atom, or a C₁₋₄alkyl-group, and
R¹ represents a hydrogen or a halogen atom or a C₁₋₄-alkyl, a C₁₋₄alkoxy or a nitro group have useful pharmaceutical activities, in particular cytoprotective and optionally antiulcer activities. They can be used in the treatment and prevention of ulceration in the digestive tract of mammals, inclusive men.
wherein
n is an integer of from 0 to 2,
R represents a hydrogen, an alkaline or an alkaline earth metal atom, or a C₁₋₄alkyl-group, and
R¹ represents a hydrogen or a halogen atom or a C₁₋₄-alkyl, a C₁₋₄alkoxy or a nitro group have useful pharmaceutical activities, in particular cytoprotective and optionally antiulcer activities. They can be used in the treatment and prevention of ulceration in the digestive tract of mammals, inclusive men.
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