发明公开
- 专利标题: Optically active benzyl alcohol compound and pharmaceutical composition
- 专利标题(中): 光活性苯甲醇醇化合物及其用途
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申请号: EP90118338.4申请日: 1990-09-25
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公开(公告)号: EP0420120A3公开(公告)日: 1991-09-11
- 发明人: Ito, Yasuo , Kato, Hideo , Koshinaka, Eiichi , Kurata, Sakae , Morikawa, Koji
- 申请人: HOKURIKU PHARMACEUTICAL CO., LTD.
- 申请人地址: 1-Chome, 3-14, Tatekawacho, Katsuyama-shi Fukui-ken 911 JP
- 专利权人: HOKURIKU PHARMACEUTICAL CO., LTD.
- 当前专利权人: HOKURIKU PHARMACEUTICAL CO., LTD.
- 当前专利权人地址: 1-Chome, 3-14, Tatekawacho, Katsuyama-shi Fukui-ken 911 JP
- 代理机构: Werner, Hans-Karsten, Dr.Dipl.-Chem.
- 优先权: JP250424/89 19890928; JP202476/90 19900801
- 主分类号: C07C215/60
- IPC分类号: C07C215/60 ; A61K31/135
摘要:
A levo-rotatory enantiomer of benzyl alcohol compound represented by the following formula (I):
wherein . C represents an asymmetric carbon atom; a pharmacologically acceptable salt of the compound; and a method for preparing the enantiomer is disclosed. Also disclosed are methods for ralaxing uterine smooth muscle and bladder smooth muscle comprising administering the levo-rotatory enantiomer. Further disclosed is a pharmaceutical composition for the treatment of premature labor or incontinence of urine comprising an effective amount of the levo-rotatory enantiomer together with a pharmaceutically acceptable carrier or coating. Lastly disclosed are methods for the treatment of premature labor or incontinence of urine comprising the steps of determining that a mammal has one of these illnesses and administering the levo-rotatory enantiomer to the mammal.
wherein . C represents an asymmetric carbon atom; a pharmacologically acceptable salt of the compound; and a method for preparing the enantiomer is disclosed. Also disclosed are methods for ralaxing uterine smooth muscle and bladder smooth muscle comprising administering the levo-rotatory enantiomer. Further disclosed is a pharmaceutical composition for the treatment of premature labor or incontinence of urine comprising an effective amount of the levo-rotatory enantiomer together with a pharmaceutically acceptable carrier or coating. Lastly disclosed are methods for the treatment of premature labor or incontinence of urine comprising the steps of determining that a mammal has one of these illnesses and administering the levo-rotatory enantiomer to the mammal.
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