发明公开
EP0423358A1 POSTOSTATIN AND RELATED COMPOUND THEREOF, OR THEIR SALTS
失效
维多利亚VERBINDUNG DAVON ODER DEREN SALZE。
- 专利标题： POSTOSTATIN AND RELATED COMPOUND THEREOF, OR THEIR SALTS
- 专利标题（中）： 维多利亚VERBINDUNG DAVON ODER DEREN SALZE。
-
申请号： EP90905686.3申请日： 1990-04-13
-
公开(公告)号： EP0423358A1公开(公告)日： 1991-04-24
- 发明人: TAKEUCHI, Tomio , AOYAGI, Takaaki , HAMADA, Masa , NAGANAWA, Hiroshi , MURAOKA, Yasuhiko , OGAWA, Keiji , NAGAI, Machiko,Syare Gakugeidai Kawabe 2-207 , TSUDA, Makoto, Nippon Kayaku Kabushiki Kaisha
- 申请人： ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI
- 申请人地址： 14-23, Kamiosaki 3-chome Shinagawa-ku Tokyo JP
- 专利权人： ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI
- 当前专利权人： ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI
- 当前专利权人地址： 14-23, Kamiosaki 3-chome Shinagawa-ku Tokyo JP
- 代理机构： Türk, Gille, Hrabal, Leifert
- 优先权： JP94328/89 19890415
- 国际公布： WO9012805 19901101
- 主分类号： C07K5/08
- IPC分类号： C07K5/08 ; C12P21/02 ; A61K37/02
摘要：
Postostatin, a new physiologically active substance represented by (I), can be isolated from the culture medium of an actinomycete belonging to the genus Streptomyces. It is a peptide compound having a new structure wherein a keto group is present in the peptide chain and it has a potent endopeptidase inhibitory activity. A postostatin-related compound having a keto group in the peptide chain can he synthesized chemically and this compound has a similar endopeptidase inhibitory activity.
信息查询
