发明授权
- 专利标题： ANTICORPS PURIFIES SPECIFIQUEMENT DIRIGES CONTRE LES LIPOPOLYSACCHARIDES (LPS) DES BACTERIES GRAM NEGATIF
- 专利标题（英）： Purified antibodies specifically directed against the lipopolysaccharides (lps) of gram negative bacteria
- 专利标题（中）： 对革兰阴性菌的脂多糖（LPS）的纯化抗体。
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申请号： EP91907576.2申请日： 1991-04-03
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公开(公告)号： EP0527768B1公开(公告)日： 1995-09-06
- 发明人: BASUYAUX, Bertrand , LAROZE, Alain , TRINCOT, Anne
- 申请人： FONDATION NATIONALE DE TRANSFUSION SANGUINE
- 申请人地址： 6, rue Alexandre Cabanel 75739 Paris Cédex 15 FR
- 专利权人： FONDATION NATIONALE DE TRANSFUSION SANGUINE
- 当前专利权人： FONDATION NATIONALE DE TRANSFUSION SANGUINE
- 当前专利权人地址： 6, rue Alexandre Cabanel 75739 Paris Cédex 15 FR
- 代理机构： Warcoin, Jacques
- 优先权： FR9004227 19900403
- 国际公布： WO9115239 19911017
- 主分类号： A61K39/40
- IPC分类号： A61K39/40
摘要：
The invention relates to purified antibodies specifically directed against the lipopolysaccharides (LPS) of gram negative bacteria. Said antibodies are characterized in that they are obtained in a single step, with an enrichment factor greater than 500 and preferably greater than 750, by immunoaffinity chromatography of the anti-LPS antibodies present in biological liquids which binds said antibodies to the LPS antibodies immobilized on a support. The invention also relates to pharmaceutical compositions containing said antibodies.
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