发明公开
- 专利标题： Enzymatic synthesis of chiral alpha-hydroxyketones and derivatives
- 专利标题（中）： 精氨酸羟基酮和衍生物的合成
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申请号： EP92308959.3申请日： 1992-10-01
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公开(公告)号： EP0537921A3公开(公告)日： 1993-06-16
- 发明人: Gala, Dinesh
- 申请人： SCHERING CORPORATION
- 申请人地址： 2000 Galloping Hill Road Kenilworth New Jersey 07033 US
- 专利权人： SCHERING CORPORATION
- 当前专利权人： SCHERING CORPORATION
- 当前专利权人地址： 2000 Galloping Hill Road Kenilworth New Jersey 07033 US
- 代理机构： Ritter, Stephen David
- 优先权： US771260 19911004
- 主分类号： C12P41/00
- IPC分类号： C12P41/00 ; C12P7/26 ; C12P7/62
摘要：
A process for the preparation of a chiral a-hydroxyketone, or ester thereof, comprising hydrolyzing an ester of said a-hydroxyketone with an enzyme that has a specificity for one enantiomer, or by esterifying said a-hydroxyketone with an esterifying agent in the presence of an enzyme that favors one enantiomer.
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