发明公开
EP0546939A1 Biodegradable magnetic microclusters and methods for making them
失效
Magnetische Microclusters und Verfahren zur Herstellung。
- 专利标题： Biodegradable magnetic microclusters and methods for making them
- 专利标题（中）： Magnetische Microclusters und Verfahren zur Herstellung。
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申请号： EP92403345.9申请日： 1992-12-09
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公开(公告)号： EP0546939A1公开(公告)日： 1993-06-16
- 发明人: Chagnon, Mark S. , Ferris, John R. , Fiore, Barry L. , Carter, Michelle J. , Hamilton, Tracy J.
- 申请人： MOLECULAR BIOQUEST, INC.
- 申请人地址： 8 Commerce Drive Atkinson, NH 03811 US
- 专利权人： MOLECULAR BIOQUEST, INC.
- 当前专利权人： MOLECULAR BIOQUEST, INC.
- 当前专利权人地址： 8 Commerce Drive Atkinson, NH 03811 US
- 代理机构： Des Termes, Monique
- 优先权： US806478 19911213
- 主分类号： A61K49/00
- IPC分类号： A61K49/00 ; A61K47/48
摘要：
Subdomain metal or metal oxide particles covalently coupled to chemically reactive organic moieties and subsequently reacted together to form biodegradable magnetic microclusters are disclosed. The magnetic microcluster can be used as contrast agents in NMR imaging for the production of images suitable for use in diagnosis, for in vivo delivery and targeting of drugs, as in vivo , biodegradable agents for the sequestering of free metal ions in the treatment of metal driven disease.
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