发明公开
- 专利标题： Inhibitors of farnesyl protein transferase
- 专利标题（中）： 抑制法呢基蛋白转移酶。
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申请号： EP92203807.0申请日： 1992-12-08
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公开(公告)号： EP0547670A2公开(公告)日： 1993-06-23
- 发明人: Singh, Sheo Bux , Bills, Gerald F. , Lingham, Russell B. , Silverman, Keith C. , Zink, Deborah L.
- 申请人： MERCK & CO. INC.
- 申请人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 专利权人： MERCK & CO. INC.
- 当前专利权人： MERCK & CO. INC.
- 当前专利权人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 代理机构： Barrett-Major, Julie Diane
- 优先权： US807695 19911216
- 主分类号： C07C57/13
- IPC分类号： C07C57/13 ; A61K31/19 ; C07C211/00
摘要：
This invention relates to pharmaceutical compounds of structural formula (I):
and compositions and methods of treatment utilizing these compounds to inhibit farnesyl protein transferase and farnesylation of the oncogene protein Ras.
and compositions and methods of treatment utilizing these compounds to inhibit farnesyl protein transferase and farnesylation of the oncogene protein Ras.
公开/授权文献
- EP0547670A3 Inhibitors of farnesyl protein transferase 公开/授权日：1993-08-25
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