发明授权
EP0594764B1 HEMATOPOIETIC GROWTH FACTOR DERIVED FROM T LYMPHOCYTES AND METHODS OF USE THEREFOR
失效
OFF T淋巴细胞得到的造血生长因子，及其使用方法
- 专利标题： HEMATOPOIETIC GROWTH FACTOR DERIVED FROM T LYMPHOCYTES AND METHODS OF USE THEREFOR
- 专利标题（中）： OFF T淋巴细胞得到的造血生长因子，及其使用方法
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申请号： EP92916012.5申请日： 1992-07-07
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公开(公告)号： EP0594764B1公开(公告)日： 2000-01-12
- 发明人: Choudhury, Chandra
- 申请人： Choudhury, Chandra
- 申请人地址： 1610 Robert E. Lee Blvd., Apt. 29 New Orleans, Louisiana 70122 US
- 专利权人： Choudhury, Chandra
- 当前专利权人： Choudhury, Chandra
- 当前专利权人地址： 1610 Robert E. Lee Blvd., Apt. 29 New Orleans, Louisiana 70122 US
- 代理机构： Brown, John David
- 优先权： US729135 19910712; US747784 19910819; US788115 19911101
- 国际公布： WO9300923 19930121
- 主分类号： C12N15/27
- IPC分类号： C12N15/27 ; C07K1/00 ; C07K14/00 ; C07K16/00 ; C07K17/00 ; C12N5/10 ; C12Q1/68 ; G01N33/53 ; G01N33/564 ; A61K38/00 ; C12N1/21 ; C12P21/02 ; C12P21/08 ; C12N5/00 ; G01N33/68
摘要：
A T cell-derived colony stimulating factor (TC-CSF) may be isolated from media conditioned with T lymphocyte cells. TC-CSF stimulates formation of colonies composed of granulocytes, macrophages, megakaryocytes, fibrocytic stromal cells, lymphocytes, and mixed colonies of granulocytes and macrophages. Anion exchange chromatography may be employed in conjunction with gel filtration and rpHPLC to isolate TC-CSF. Human TC-CSF and murine TC-CSF cDNA, mRNA, genomic DNA nucleotide and amino acid sequences, expression products, pharmaceutical formulations and antibody materials are specifically provided.
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