发明公开
EP0607309A1 THE REGULATION OF SYSTEMIC IMMUNE RESPONSES UTILIZING CYTOKINES AND ANTIGENS
失效
调节免疫应答BYSYSTÄMISCHEN细胞因子和抗原。
- 专利标题： THE REGULATION OF SYSTEMIC IMMUNE RESPONSES UTILIZING CYTOKINES AND ANTIGENS
- 专利标题（中）： 调节免疫应答BYSYSTÄMISCHEN细胞因子和抗原。
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申请号： EP92921896.0申请日： 1992-10-05
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公开(公告)号： EP0607309A1公开(公告)日： 1994-07-27
- 发明人: DRANOFF, Glenn , MULLIGAN, Richard C. , PARDOLL, Drew
- 申请人： WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH , THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
- 申请人地址： Nine Cambridge Center Cambridge, MA 02142 US
- 专利权人： WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH,THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
- 当前专利权人： WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH,THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
- 当前专利权人地址： Nine Cambridge Center Cambridge, MA 02142 US
- 代理机构： Holdcroft, James Gerald, Dr., et al
- 优先权： US19910771194 19911004
- 国际公布： WO1993006867 19930415
- 主分类号： C12N15
- IPC分类号： C12N15 ; A61K35 ; A61K38 ; A61K39 ; A61P35 ; A61P37 ; C07K14 ; C12N5 ; C12P21 ; A61K48 ; C12R1
摘要：
A method of altering the specific, systemic immune response of an individual to a target antigen by the co-administration of a cytokine an adhesion or accessory molecule and the target antigen. The target antigen may be a tumor cell, a tumor cell antigen, an infectious agent or other foreign antigen, or other antigens to which an enchanted systemic immune response is desirable. Alternatively, the antigen may be a non-foreign antigen when a suppression of a systemic immune response is desired. The resulting systemic immune response is specific for the target antigen.
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