发明授权
- 专利标题: WIRKSTOFF-ENTHALTENDE FESTKÖRPER MIT EINEM GERÜST AUS HYDROPHILEN MAKROMOLEKÜLEN UND VERFAHREN ZU IHRER HERSTELLUNG
- 专利标题(英): Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
- 专利标题(中): ACTIVE-含有固体带支架关闭生产亲水性大分子和过程
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申请号: EP93902034.3申请日: 1993-01-18
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公开(公告)号: EP0621777B1公开(公告)日: 1996-09-11
- 发明人: WUNDERLICH, Jens-Christian , SCHICK, Ursula , WERRY, Jürgen , FREIDENREICH, Jürgen
- 申请人: ALFATEC-PHARMA GmbH
- 申请人地址: Im Neuenheimer Feld 519 D-69120 Heidelberg DE
- 专利权人: ALFATEC-PHARMA GmbH
- 当前专利权人: ALFATEC-PHARMA GmbH
- 当前专利权人地址: Im Neuenheimer Feld 519 D-69120 Heidelberg DE
- 代理机构: KUHNEN, WACKER & PARTNER
- 优先权: DE4201179 19920117; DE4201173 19920117; US876864 19920430; US876877 19920430
- 国际公布: WO9313757 19930722
- 主分类号: A61K9/20
- IPC分类号: A61K9/20 ; A61K9/16
摘要:
The invention concerns precisely meterable moulded bodies, for instance granules or pellets, containing hydrophilic macromolecules, active substances and, optionally, other pharmaceutically acceptable structure-forming agents and auxiliaries, the active substance being dissolved in, suspended in or emulsified with a matrix. The invention also concerns a method for producing such moulded bodies, the method being particularly cost-effective and environmentally acceptable, and the use of the moulded bodies as drugs in which bio-availability, storability and compatability are increased. In addition, the moulded bodies described, or mixtures of them, are also useful in preparing intermediates or end-products for use in pharmaceutics, cosmetics, diagnosis, analysis or dietary health care.
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