发明公开
- 专利标题: Esculetin derivatives and method for manufacture thereof, use thereof, and pharmaceutical composition
- 专利标题(中): 七叶亭衍生物及其制造方法,其用途和药物组合物
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申请号: EP94118020.0申请日: 1994-11-15
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公开(公告)号: EP0654479A3公开(公告)日: 1995-09-13
- 发明人: Watanabe, Koju , Niimura, Koichi , Miyagawa, Junko
- 申请人: KUREHA CHEMICAL INDUSTRY CO., LTD.
- 申请人地址: 9-11, Nihonbashi Horidomecho 1 chome Chuo-ku Tokyo JP
- 专利权人: KUREHA CHEMICAL INDUSTRY CO., LTD.
- 当前专利权人: KUREHA CHEMICAL INDUSTRY CO., LTD.
- 当前专利权人地址: 9-11, Nihonbashi Horidomecho 1 chome Chuo-ku Tokyo JP
- 代理机构: Minderop, Ralph H., Dr. rer. nat.
- 优先权: JP308779/93 19931115
- 主分类号: C07H17/075
- IPC分类号: C07H17/075 ; A61K31/70
摘要:
A compound of the formula (I):
wherein R¹ and R² are, independently, a hydrogen atom, a monosaccharide residue, a protected monosaccharide residue, or a protecting group for hydroxyl group, but at least one of R¹ and R² is a monosaccharide residue or a protected monosaccharide residue, and R³ is a hydrogen atom, a hydroxyl group, an alkyl group, an aryl group, or an aralkyl group, with the proviso that (1) when R¹ and R² are glucose residues at the same time, R³ is not a hydrogen atom, (2) when R¹ is a hydrogen atom, an acetyl group or a benzyl group and R² is a glucose residue, an acetylated glucose residue, or acetalized glucose residue, R³ is not a hydrogen atom, or (3) when R¹ is a glucose residue and R² is a hydrogen atom, R³ is not a hydrogen atom or a salt thereof is disclosed.
wherein R¹ and R² are, independently, a hydrogen atom, a monosaccharide residue, a protected monosaccharide residue, or a protecting group for hydroxyl group, but at least one of R¹ and R² is a monosaccharide residue or a protected monosaccharide residue, and R³ is a hydrogen atom, a hydroxyl group, an alkyl group, an aryl group, or an aralkyl group, with the proviso that (1) when R¹ and R² are glucose residues at the same time, R³ is not a hydrogen atom, (2) when R¹ is a hydrogen atom, an acetyl group or a benzyl group and R² is a glucose residue, an acetylated glucose residue, or acetalized glucose residue, R³ is not a hydrogen atom, or (3) when R¹ is a glucose residue and R² is a hydrogen atom, R³ is not a hydrogen atom or a salt thereof is disclosed.
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