发明授权
EP0665890B1 INCREASED PRODUCTION OF SECRETED PROTEINS BY RECOMBINANT EUKARYOTIC CELLS
失效
通过重组的真核细胞分泌的蛋白质的产生增加
- 专利标题: INCREASED PRODUCTION OF SECRETED PROTEINS BY RECOMBINANT EUKARYOTIC CELLS
- 专利标题(中): 通过重组的真核细胞分泌的蛋白质的产生增加
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申请号: EP93921939.0申请日: 1993-10-06
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公开(公告)号: EP0665890B1公开(公告)日: 2003-11-19
- 发明人: KERÄNEN, Sirkka , AALTO, Markku , OUTOLA, Mika , RONNE, Hans , PENTTILÄ, Merja
- 申请人: VALTION TEKNILLINEN TUTKIMUSKESKUS
- 申请人地址: Vuorimiehentie 5 02150 Espoo 15 FI
- 专利权人: VALTION TEKNILLINEN TUTKIMUSKESKUS
- 当前专利权人: VALTION TEKNILLINEN TUTKIMUSKESKUS
- 当前专利权人地址: Vuorimiehentie 5 02150 Espoo 15 FI
- 代理机构: Polz, Leo, Dr.
- 优先权: FI924494 19921006
- 国际公布: WO94008024 19940414
- 主分类号: C12N15/80
- IPC分类号: C12N15/80 ; C12N15/67 ; C12P21/02
摘要:
The invention relates to recombinant DNA technology. Specifically this invention relates to new recombinant eukaryotic cells transformed with SSO genes. Eukaryotic cells transformed with several copies of SSO genes, or overexpressing the Sso protein by some other means, have an increased capacity to produce secreted foreign or endogenous proteins. Further, the said new recombinant cells, when transformed with genes expressing suitable hydrolytic enzymes can utilize appropriate macromolecular compounds more efficiently, which results in increased cell mass production and/or more versatile utilization of the compounds in relevant biotechnical applications.
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