发明公开
- 专利标题: SYSTEMS AND METHODS FOR RESUSPENDING CELLULAR-RICH CONCENTRATES.
- 专利标题(中): 系统和再悬浮细胞富集的浓缩物的方法。
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申请号: EP94916495申请日: 1994-02-14
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公开(公告)号: EP0666770A4公开(公告)日: 1998-08-19
- 发明人: BROWN RICHARD I
- 申请人: BAXTER INT
- 专利权人: BAXTER INT
- 当前专利权人: BAXTER INT
- 优先权: US9729393 1993-07-26
- 主分类号: A61M1/02
- IPC分类号: A61M1/02 ; A61K35/14 ; A61M1/36 ; B01D21/26 ; B04B5/00 ; B04B5/04 ; A61M1/00 ; B04B11/00
摘要:
Systems and methods for resuspending cellular-rich concentrates of blood are disclosed. Systems include first compartment (24) including a blood inlet port (40) and a plasma-rich platelets (PRP) collection port (38) and a red blood cell collection port (42), and second compartment (26) including a platelet-poor plasma (PPP) collection port (44) and a leukocyte-depleted PRP (LDPRP) inlet port (46), and a separation element (14). In resuspension mode, a volume of retained PPP is returned through the PPP collection port (44) into the second compartment (26) to mix with and resuspend leukocyte-depleted platelet concentrate (LDPC) in the second compartment (26). During the resuspension period, a rotor (28) slowly oscillates the second compartment (26) first in one rotational direction and then in an opposite rotational direction. The oscillation creates variable agitation forces that aid the mixing and resuspension process within the second compartment (26).
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