An economically excellent and efficient process for producing a 3-amino-2-hydroxy-1-propanol derivative, represented by general formula (2), useful as an intermediate for producing medicines, such as an HIV protease inhibitor, and an oxazolidinone derivative derived therefrom, wherein R¹ represents alkyl, aralkyl or aryl; and R² and R³ represent each independently hydrogen or an amino-protecting group, provided the case where both of R² and R³ represent hydrogen is excluded.