发明公开
- 专利标题: PYRAZOLE DERIVATIVE
- 专利标题(中): 吡唑衍生物
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申请号: EP94912072申请日: 1994-04-07
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公开(公告)号: EP0693480A4公开(公告)日: 1996-09-25
- 发明人: TANIKAWA KEIZO , KAMIKAWAJI YOSHIMASA , ODOI KEISUKE , HIGASHIYAMA TSUTOMU , SATO MASAYUKI , MASUDA YUKINORI
- 申请人: NISSAN CHEMICAL IND LTD
- 专利权人: NISSAN CHEMICAL IND LTD
- 当前专利权人: NISSAN CHEMICAL IND LTD
- 优先权: JP8092293 1993-04-07; JP91794 1994-01-10
- 主分类号: C07D231/38
- IPC分类号: C07D231/38 ; C07D401/14 ; C07D403/12 ; C07D403/14 ; C07D405/12 ; C07D405/14 ; C07D409/12 ; C07D409/14 ; C07F9/6558 ; A61K31/415 ; A61K31/675 ; C07D231/40 ; C07D401/00 ; C07D403/00 ; C07D405/00 ; C07D409/00 ; C07D413/00 ; C07F9/6503 ; C07H19/02
摘要:
A pyrazole compound represented by general formula (1), tautomers thereof, and salts of both; (wherein R1 represents alkyl, etc.; R2 represents carboxyl, etc.; R3 represents halogen, alkyl, phenyl, etc.; R?4, R5 and R6¿ represent each hydrogen, halogen, etc.; R7 represents carboxyl, 5-tetrazolyl, etc.; X represents nitrogen, etc.; Y and Z represent each CH, nitrogen, etc.; A and E represent each methylene, etc.; D represents phenyl, etc.; and G represents a covalent bond, etc.), having angiotensin II antagonism and being useful for preventing or treating hypertension, congestive heart failure, chronic renal failure, aldosteronism, increased intraocular pressure, and so forth.
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