发明公开
EP0713533A1 BIOCATALYTIC METHODS FOR SYNTHESIZING AND IDENTIFYING BIOLOGICALLY ACTIVE COMPOUNDS
失效
生物催化METODEN法合成和确定生物活性化合物
- 专利标题： BIOCATALYTIC METHODS FOR SYNTHESIZING AND IDENTIFYING BIOLOGICALLY ACTIVE COMPOUNDS
- 专利标题（中）： 生物催化METODEN法合成和确定生物活性化合物
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申请号： EP94925870.0申请日： 1994-08-12
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公开(公告)号： EP0713533A1公开(公告)日： 1996-05-29
- 发明人: FOX, J. Wesley , DORDICK, Jonathan S. , CLARK, Douglas S.
- 申请人： ENZYMED, Inc.
- 申请人地址： Suite C-100, 2501 Crosspark, Oakdale Research Park Iowa City, IA 52242-5000 US
- 专利权人： ENZYMED, Inc.
- 当前专利权人： ENZYMED, Inc.
- 当前专利权人地址： Suite C-100, 2501 Crosspark, Oakdale Research Park Iowa City, IA 52242-5000 US
- 代理机构： Orès, Bernard, et al
- 优先权： US19930106279 19930813
- 国际公布： WO1995005475 19950223
- 主分类号： G01N33
- IPC分类号： G01N33 ; B01J19 ; C07K1 ; C12P1 ; G01N35
摘要：
This invention encompasses methods for producing a library of modified starting compounds by use of biocatalytic reactions on a starting compound and identifying the modified starting compound with the optimum desired activity. The invention encompasses starting compounds and modified compounds that are free in solution. The method is useful in producing modified pharmaceutical compounds with desired specific activity.
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