发明公开
EP0719339A1 SUBTILISIN BPN' VARIANTS WITH DECREASED ADSORPTION AND INCREASED HYDROLYSIS
失效
枯草杆菌蛋白酶BPN“具有降低吸附和增加的水解选项
- 专利标题： SUBTILISIN BPN' VARIANTS WITH DECREASED ADSORPTION AND INCREASED HYDROLYSIS
- 专利标题（中）： 枯草杆菌蛋白酶BPN“具有降低吸附和增加的水解选项
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申请号： EP94929758.0申请日： 1994-08-31
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公开(公告)号： EP0719339A1公开(公告)日： 1996-07-03
- 发明人: BRODE, Philip, Frederick, III , BARNETT, Bobby, Lee , RUBINGH, Donn, Nelton
- 申请人： THE PROCTER & GAMBLE COMPANY
- 申请人地址： One Procter & Gamble Plaza Cincinnati, Ohio 45202 US
- 专利权人： THE PROCTER & GAMBLE COMPANY
- 当前专利权人： THE PROCTER & GAMBLE COMPANY
- 当前专利权人地址： One Procter & Gamble Plaza Cincinnati, Ohio 45202 US
- 代理机构： Engisch, Gautier, et al
- 优先权： US19930121437 19930915; US19940287461 19940811
- 国际公布： WO1995007991 19950323
- 主分类号： C12N15
- IPC分类号： C12N15 ; A61K8 ; A61Q11 ; C07K14 ; C11D3 ; C11D17 ; C12N9 ; C12R1
摘要：
The present invention relates to subtilisin BPN' variants comprising at least one or more amino acid positions having a different amino acid than that occurring in wild-type subtilisin BPN' (i.e., substitution) at positions 199-220 whereby the BPN' variant has decreased adsorption to, and increased hydrolysis of, an insoluble substrate as compared to wild-type subtilisin BPN'.
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