发明授权
- 专利标题： STABLE SOLVATES OF AVERMECTIN COMPOUNDS
- 专利标题（中）： 稳定的溶剂化物阿维菌素联系
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申请号： EP94931307.6申请日： 1994-10-04
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公开(公告)号： EP0722454B1公开(公告)日： 1999-05-12
- 发明人: AMATO, Joseph, S. , CVETOVICH, Raymond
- 申请人： Merck & Co., Inc.
- 申请人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 代理机构： Hiscock, Ian James
- 优先权： US133494 19931008
- 国际公布： WO9510525 19950420
- 主分类号： C07H19/01
- IPC分类号： C07H19/01 ; A01N43/90 ; C07D493/22 ; A61K31/365
摘要：
There is disclosed a novel form of avermectin compounds wherein the avermectin compounds are crystallized as alcohol solvates to greatly enhance stability of the avermectin drug during long-term storage. The avermectin compounds have utility as highly potent antiparasitic, insecticidal, and anthelmintic agents and compositions for that use are also disclosed.
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