发明公开
- 专利标题: ADENOVIRUS RECOMBINANTS INTEGRATIFS, LEUR PREPARATION ET LEUR UTILISATION THERAPEUTIQUE
- 专利标题(英): Integrative recombinant adenoviruses, preparation thereof and therapeutical uses thereof
- 专利标题(中): 端到端集成重组腺病毒及其制备和治疗用途
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申请号: EP95910605.0申请日: 1995-02-28
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公开(公告)号: EP0748385A1公开(公告)日: 1996-12-18
- 发明人: DENEFLE, Patrice , LATTA, Martine , PERRICAUDET, Michel , VIGNE, Emmanuelle
- 申请人: RHONE-POULENC RORER S.A.
- 申请人地址: 20, avenue Raymond Aron 92160 Antony FR
- 专利权人: RHONE-POULENC RORER S.A.
- 当前专利权人: RHONE-POULENC RORER S.A.
- 当前专利权人地址: 20, avenue Raymond Aron 92160 Antony FR
- 代理机构: Becker, Philippe
- 优先权: FR19940002445 19940303
- 国际公布: WO1995023867 19950908
- 主分类号: C12N15
- IPC分类号: C12N15 ; A61K9 ; A61K35 ; A61K38 ; A61K48 ; A61P9 ; A61P25 ; A61P31 ; A61P35 ; A61P37 ; C07K14 ; C12N5 ; C12N7
摘要:
Recombinant adenoviruses comprising a cassette which can be integrated into the genome of infected cells, the preparation thereof, pharmaceutical compositions containing same, and uses of said adenoviruses, are disclosed. The cassette particularly contains at least one inverted terminal repeat (ITR) of an AAV and a heterologous DNA sequence.
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