-
1.发明公开ADENOVIRUS RECOMBINANTS, LEUR UTILISATION POUR PREPARER DES AAV, LIGNEE CELLULAIRE COMPLEMENTAIRE ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT 失效重组腺病毒，它们在AAV生产，进行互补FALIGE CELL LINE和含有药物组合物
公开(公告)号：EP0833896A1
公开(公告)日：1998-04-08
申请号：EP96922971.0
申请日：1996-06-20
发明人： LATTA, Martine , ORSINI, Cécile , PERRICAUDET, Michel , PROST, Edouard , VIGNE, Emmanuelle , YEH, Patrice
CPC分类号： C12N15/86 , C12N15/63 , C12N2710/10343 , C12N2710/10344 , C12N2710/16622 , C12N2750/14122 , C12N2750/14143 , C12N2830/003 , C12N2830/15
摘要： A recombinant adenovirus in which the expression of a nucleic acid sequence coding for at least one homologous or heterologous gene of viral origin is placed under the control of an inducible promoter, is disclosed. The use of such recombinant adenoviruses for preparing AAVs, and a complementary cell line and preparation method therefor, are also disclosed. Furthermore, pharmaceutical compositions containing such an adenovirus are disclosed.
-
公开(公告)号：EP0805868A1
公开(公告)日：1997-11-12
申请号：EP96901417.0
申请日：1996-01-19
发明人： DEDIEU, Jean-François , LATTA, Martine , ORSINI, Cécile , PERRICAUDET, Michel , VIGNE, Emmanuelle , YEH, Patrice , PROST, Eduard
CPC分类号： C12N15/86 , C12N7/00 , C12N2710/10322 , C12N2710/10343 , C12N2710/10362 , C12N2750/14143 , C12N2830/002
摘要： The invention relates to cells usable for the production of defective adenoviruses comprising, inserted into their genome, a portion of the region E4 of an adenovirus genome carrying the reading phase ORF6 under the control of a functional promoter.
-
3.发明公开ADENOVIRUS RECOMBINANTS INTEGRATIFS, LEUR PREPARATION ET LEUR UTILISATION THERAPEUTIQUE 失效端到端集成重组腺病毒及其制备和治疗用途
公开(公告)号：EP0748385A1
公开(公告)日：1996-12-18
申请号：EP95910605.0
申请日：1995-02-28
IPC分类号： C12N15 , A61K9 , A61K35 , A61K38 , A61K48 , A61P9 , A61P25 , A61P31 , A61P35 , A61P37 , C07K14 , C12N5 , C12N7
CPC分类号： C12N15/86 , A61K38/00 , A61K48/00 , C07K14/775 , C12N7/00 , C12N2710/10343 , C12N2710/10344 , C12N2710/10362 , C12N2750/14143 , C12N2830/008
摘要： Recombinant adenoviruses comprising a cassette which can be integrated into the genome of infected cells, the preparation thereof, pharmaceutical compositions containing same, and uses of said adenoviruses, are disclosed. The cassette particularly contains at least one inverted terminal repeat (ITR) of an AAV and a heterologous DNA sequence.
-
4.发明公开POLYPEPTIDES DERIVES DE L'APOLIPOPROTEINE AIV HUMAINE, LEUR PREPARATION ET LEUR UTILISATION 失效从mensliche载脂蛋白禽流感病毒的多肽，其制备及其用途。
公开(公告)号：EP0624194A1
公开(公告)日：1994-11-17
申请号：EP93904117.0
申请日：1993-01-26
发明人： DENEFLE, Patrice , GUINET, Françoise , LATTA, Martine , MURRY-BRELIER, Anne, Résidence Le Renouveau
CPC分类号： C07K14/775 , A61K38/00
摘要： La présente invention concerne des polypeptides dérivés de l'apolipoprotéine AIV humaine (apoAIV), les séquences nucléotidiques codant pour ces polypeptides, leur préparation et leur utilisation.
-
-
-
搜索结果
4 条记录 (耗时 0.017 秒)
