发明公开
- 专利标题: HETEROCYCLIC COMPOUND
- 专利标题(中): 杂环E
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申请号: EP95909107.5申请日: 1995-02-17
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公开(公告)号: EP0748808A1公开(公告)日: 1996-12-18
- 发明人: OHUCHI, Yutaka Taisho Pharmaceutical Co., Ltd. , SUZUKI, Masaji Taisho Pharmaceutical Co., Ltd. , ASANUMA, Hajime Taisho Pharmaceutical Co., Ltd. , YOKOMORI, Sadakazu Taisho Pharmaceutical Co.,Ltd. , HATAYAMA, Katsuo Taisho Pharmaceutical Co., Ltd. , ISOBE, Yoshihiko Taisho Pharmaceutical Co., Ltd. , KIJIMA, Haruko Taisho Pharmaceutical Co., Ltd. , MURAMATSU, Makoto Taisho Pharmaceutical Co., Ltd.
- 申请人: TAISHO PHARMACEUTICAL CO. LTD
- 申请人地址: 24-1 Takata 3-chome Toshima-ku Tokyo 171 JP
- 专利权人: TAISHO PHARMACEUTICAL CO. LTD
- 当前专利权人: TAISHO PHARMACEUTICAL CO. LTD
- 当前专利权人地址: 24-1 Takata 3-chome Toshima-ku Tokyo 171 JP
- 代理机构: Kraus, Walter, Dr.
- 优先权: JP30119/94 19940228
- 国际公布: WO9523147 19950831
- 主分类号: C07D471/18
- IPC分类号: C07D471/18 ; A61K31/47
摘要:
Endo-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl) 1-isopropyl-2(1H)-quinolone-3-carboxylate represented by Formula (I):
or an acid addition salt thereof acts on a serotonin 4 receptor thereby to have a serotonin-like receptor stimulating activity, therefore has an action on activating gastrointestinal motor functions and thus is effective for the improvement of gastrointestinal conditions such as heartburn, anorexia, bowel pain or abdominal distension accompanied by chronic gastritis or postoperative gastroparesis, and further for the treatment of gastro-esophagal reflux, intestinal pseudo-obstruction or constipation.
or an acid addition salt thereof acts on a serotonin 4 receptor thereby to have a serotonin-like receptor stimulating activity, therefore has an action on activating gastrointestinal motor functions and thus is effective for the improvement of gastrointestinal conditions such as heartburn, anorexia, bowel pain or abdominal distension accompanied by chronic gastritis or postoperative gastroparesis, and further for the treatment of gastro-esophagal reflux, intestinal pseudo-obstruction or constipation.
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