In a splash-proof, modular fuse-holder a fuse-holder body (1) is closed by a removable cover (15) with the interposition of a seal (22) and the cover is engaged removably on the body by a pair of teeth (32, 33) each having a retaining side with a negative rake, cooperating with retaining teeth (24, 25) of the body (1) also each having a retaining side with a negative rake, the teeth of the cover being formed at the ends of two arms (26, 27) fixed to the cover and forming first-order levers which are biased towards the engagement position and are operable manually in order to release the cover, protective shields (34, 35, 36, 37) being disposed beside the levers to prevent adjacent fuse-holders from being opened accidentally. A coloured block (41) housed inside the body and visible when the cover is removed identifies, by its colour, the amperage of the fuse to be housed in the fuse-holder.