发明公开
- 专利标题： GENETIC DIAGNOSIS OF PROSTATE CANCER
- 专利标题（中）： 前列腺癌的基因诊断
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申请号： EP95927253.0申请日： 1995-07-18
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公开(公告)号： EP0771362A1公开(公告)日： 1997-05-07
- 发明人: NELSON, William, G. , ISAACS, William, B. , LEE, Wen-Hsiang
- 申请人： THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
- 申请人地址： 720 Rutland Avenue Baltimore, MD 21205 US
- 专利权人： THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
- 当前专利权人： THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
- 当前专利权人地址： 720 Rutland Avenue Baltimore, MD 21205 US
- 代理机构： VOSSIUS & PARTNER
- 优先权： US19940277202 19940719
- 国际公布： WO1996002674 19960201
- 主分类号： C12N9
- IPC分类号： C12N9 ; C12N15 ; C12Q1 ; G01N33 ; A61K48
摘要：
A method for detecting and a method for treating a cell proliferative disorder associated with glutathione-S-transferase (GSTP1) expression is provided. The method includes direct detection of a hypermethylated GSTP1 promoter, or indirect detection of decreased GSTP1 mRNA or GSTP1 protein in a suspect tissue sample.
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