发明公开
- 专利标题： DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS
- 专利标题（中）： 药物预防复发性疱疹病毒感染
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申请号： EP95944530.0申请日： 1995-12-28
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公开(公告)号： EP0794781A1公开(公告)日： 1997-09-17
- 发明人: WRIGHT, George, E.
- 申请人： UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER
- 申请人地址： 55 Lake Avenue North Worcester, MA 01655 US
- 专利权人： UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER
- 当前专利权人： UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER
- 当前专利权人地址： 55 Lake Avenue North Worcester, MA 01655 US
- 代理机构： Vossius, Volker, Dr., et al
- 优先权： US19940365769 19941229
- 国际公布： WO1996020711 19960711
- 主分类号： C07D473
- IPC分类号： C07D473 ; A61K31 ; A61P31 ; C07H19
摘要：
N2-substituted alkylguanines and N2-substituted phenylguanine compounds which prevent recurrent herpes simplex infections are disclosed. By virtue of their ability to inhibit herpes virus thymidine kinase in vivo, such compounds will prevent, reduce the frequency of, or reduce the severity of recurrent HSV infections in humans.
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