发明授权
EP0801679B1 MONOCLONAL ANTIBODIES WHICH PROMOTE CENTRAL NERVOUS SYSTEM REMYELINATION
失效
MONOKLONALE防盗器DIE DIE REMYELINISIERUNG DES ZENTRALNERVENSYSTEMSFÖRDERN
- 专利标题: MONOCLONAL ANTIBODIES WHICH PROMOTE CENTRAL NERVOUS SYSTEM REMYELINATION
- 专利标题(中): MONOKLONALE防盗器DIE DIE REMYELINISIERUNG DES ZENTRALNERVENSYSTEMSFÖRDERN
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申请号: EP95917195.0申请日: 1995-04-27
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公开(公告)号: EP0801679B1公开(公告)日: 2005-03-09
- 发明人: RODRIGUEZ, Moses , MILLER, David, J.
- 申请人: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
- 申请人地址: Mayo Clinic 200 First Street S.W. Rochester, MN 55905 US
- 专利权人: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
- 当前专利权人: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
- 当前专利权人地址: Mayo Clinic 200 First Street S.W. Rochester, MN 55905 US
- 代理机构: Mercer, Christopher Paul
- 优先权: US236520 19940429
- 国际公布: WO1995030004 19951109
- 主分类号: C12N15/13
- IPC分类号: C12N15/13 ; A61K39/395 ; C07K16/18 ; C12N5/20 ; C12N5/06
摘要:
Monoclonal IgM antibodies which promote central nervous system remyelination when given to a mammal afflicted with a demyelinating disease are disclosed. These antibodies show multi-organ autoreactivity, and recognize both surface and cytoplasmic determinants on glial cells.
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