发明授权
EP0802917B1 ARYL SUBSTITUTED 5,5 FUSED AROMATIC NITROGEN COMPOUNDS AS ANTI-INFLAMMATORY AGENTS
失效
芳基取代的5,5-连接的芳族硝基化合物用作抗炎活性成分
- 专利标题： ARYL SUBSTITUTED 5,5 FUSED AROMATIC NITROGEN COMPOUNDS AS ANTI-INFLAMMATORY AGENTS
- 专利标题（中）： 芳基取代的5,5-连接的芳族硝基化合物用作抗炎活性成分
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申请号： EP96900215.3申请日： 1996-01-10
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公开(公告)号： EP0802917B1公开(公告)日： 2001-11-07
- 发明人: GAUTHIER, Jacques, Yves , LAU, Cheuk, K. , LEBLANC, Yves , LI, Chun-Sing , ROY, Patrick , THERIEN, Michel , WANG, Zhaoyin
- 申请人： Merck Frosst Canada & Co.
- 申请人地址： Purdy's Wharf Tower One, 1959 upper Water Street, P.O. Box 997 Halifax, Nova Scotia B3J 2X2 CA
- 专利权人： Merck Frosst Canada & Co.
- 当前专利权人： Merck Frosst Canada & Co.
- 当前专利权人地址： Purdy's Wharf Tower One, 1959 upper Water Street, P.O. Box 997 Halifax, Nova Scotia B3J 2X2 CA
- 代理机构： Cole, William Gwyn
- 优先权： US371179 19950111
- 国际公布： WO9621667 19960718
- 主分类号： C07D513/04
- IPC分类号： C07D513/04 ; C07D487/04 ; A61K31/425 ; A61K31/41
摘要：
The invention encompasses the novel compound of formula (I) as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of formula (I).
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